This volume showcases reprints of 20 significant papers published by scientists while at Cold Spring Harbor Laboratory, with a non-technical explanation of the work's significance at the time and a profile of the investigator concerned.
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Prologue: How the Laboratory Was Planted at Cold Spring Harbor and Why It Grew Therep. xv
Ecology, Adaptation, and Evolution--Early Research at Cold Spring Harborp. 1
The Animal Ecology of the Cold Spring Sand Spit, with Remarks on the Theory of Adaptation 1903C.B. Davenport
The Early Applications of Mendel's Genetics to Human Beingsp. 23
Heredity of Eye-Color in Man 1907G.C. Davenport and C.B. Davenport
The Development of Hybrid Corn at Cold Spring Harborp. 29
The Composition of a Field of Maize 1908G.H. Shull
A Pure-line Method in Corn Breeding 1909G.H. Shull
Chromosomal Changes and Heredityp. 47
Chromosomal Duplication and Mendelian Phenomena in Datura Mutants 1920A.F. Blakeslee and J. Belling and M.E. Farnham
Mouse Headquarters, Cold Spring Harborp. 53
The Heredity of Susceptibility to a Transplantable Sarcoma (J.W.B.) of the Japanese Waltzing Mouse 1920C.C. Little
Studies on Leukemia in Mice: I: The Experimental Transmission of Leukemia 1930M.N. Richter and E.C. MacDowell
Unstable Genes in Drosophilap. 77
Reddish--A Frequently "Mutating" Character in Drosophila virilis 1926M. Demerec
Quantitative Biology Comes to the Biological Laboratory--Isolating Hormonesp. 87
The Treatment of Patients with Addison's Disease with the "Cortical Hormone" of Swingle and Pfiffner 1930L.G. Rowntree and C.H. Greene and W.W. Swingle and J.J. Pfiffner
The Genetics of Taste and Smellp. 95
Genetics of Sensory Thresholds: Taste for Phenylthiocarbamide 1932A.F. Blakeslee
Pigeons, Hormones, and Lactationp. 109
A New Hormone of the Anterior Pituitary 1932O. Riddle and R.W. Bates and S.W. Dykshorn
Quantitative Biology: Biophysics in the Biological Laboratoryp. 117
Electric Impedance of Suspensions of Yeast Cells 1934H. Fricke and H.J. Curtis
Broken Chromosomesp. 125
The Fusion of Broken Ends of Chromosomes following Nuclear Fusion 1942B. McClintock
Penicillin: The Department of Genetics at Warp. 135
Production of Penicillin. United States Patent 1948M. Demerec
Development of a High-yielding Strain of Penicillium 1945M. Demerec
The Unstable Genome--Movable Genesp. 145
Chromosome Organization and Genic Expression 1951B. McClintock
Dissecting the Bacteriophage Life Cyclep. 185
The Intracellular Growth of Bacteriophages. I. Liberation of Intracellular T4 by Premature Lysis with Another Phage or with Cyanide 1952A. Doermann
The Hershey-Chase Experimentp. 201
Independent Functions of Viral Protein and Nucleic Acid in Growth of Bacteriophage 1952A. Hershey and M. Chase
Assembly Line Genesp. 223
Tryptophan Mutants in Salmonella typhimurium 1956M. Demerec and Z. Hartman
First Glimpses of DNA Repairp. 257
Time, Temperature, and Protein Synthesis: A Study of Ultraviolet-induced Mutation in Bacteria 1956E.M. Witkin
DNA and the T2 Phage Chromosomep. 279
An Estimate of the Length of the DNA Molecule of T2 Bacteriophage by Autoradiography 1961J. Cairns
The Sticky Ends of Phage [lambda] and Their Usesp. 291
Cohesion of DNA Molecules Isolated from Phage Lambda 1963A.D. Hershey and E. Burgi and L. Ingraham
DNA Synthesis and the Case of the Missing Enzymep. 303
Isolation of an E. coli Strain with a Mutation Affecting DNA Polymerase 1969P. De Lucia and J. Cairns
AppendicesDirectors at Cold Spring Harbor
Charles B. Davenportp. 311
Charles Benedict Davenport 1866-1944. A Study of Conflicting Influences 1946E.C. MacDowell
Reginald G. Harrisp. 361
Reginald Harris and the Biological Laboratory 1982
Milislav Demerecp. 367
Milislav Demerec 1895-1966 1971B. Wallace
Name Indexp. 373
Subject Indexp. 379
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